Skip to content
LVRC

Methodology & biomarkers

Patented quantitative evaluation

Our methodology is patent-licensed from the KNU College of Veterinary Medicine. Both safety and palatability evaluations use quantitative metrics to ensure objectivity and reproducibility.

Safety Score

Safety Score

Pre- and post-feeding hematology and serum-chemistry biomarkers are scored two ways in parallel; the lower of the two is taken per biomarker for a conservative posture.

  1. 01

    Reference-range deviation

    Static metric

    Scores how far each measurement falls outside its clinical reference interval. Full marks if within range; deductions scale with deviation.

  2. 02

    Rate of change

    Dynamic metric

    Scores the rate of change from baseline. Even values within the normal range receive deductions if the change is sharp.

RuleTake the lower of the two scores per biomarker. Clinically critical biomarkers (Hb, HCT, Albumin, ALP) carry a weight of 2.

Palatability Score

Palatability Score

Beyond "did they eat it," three quantitative metrics ensure objectivity.

  1. 01

    Consumption

    C(%) = (P − R) / P × 100

    Subtracts the leftover (R) from the served amount (P) to compute the actual consumption ratio.

  2. 02

    Eating time

    Time to complete intake within a fixed window

    Higher preference correlates with shorter eating time.

  3. 03

    Approach latency

    Time from offering to first bite

    Quantifies olfactory and visual appeal.

RuleAveraged across a 5-day repeat design. One-Bowl is the standard protocol.

120+ Biomarkers

Efficacy domains - 9 categories · 120+ biomarkers

Each efficacy category has its own validated biomarker panel.

  1. 01Skin & coat
  2. 02Blood glucose
  3. 03Antioxidant
  4. 04Immune
  5. 05Body weight
  6. 06Joint
  7. 07Renal
  8. 08Digestive
  9. 09Ocular (tear volume, eye fatigue)

Ready to commission a study or join an R&D project?

Our team responds within 1–2 business days.

Request a project